商品属性：
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产品名称
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ANGEL1抗体
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英文名称
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ANGEL1
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产品规格
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50ul 100ul 200ul
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产品货号
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GOY-01K1015
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产品分类
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抗体 / 一抗
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交叉反应
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Human, Mouse, Rat, Cow, Horse, Sheep
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保存条件
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Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
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标记
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Unconjugated
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抗体来源
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Rabbit
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抗体类型
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Polyclonal
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研究领域
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肿瘤 细胞生物 神经生物学
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蛋白细胞定位
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细胞核,细胞浆
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纯化方法
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affinity purified by Protein A
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性状
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Liquid
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浓度
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1mg/ml
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储存液
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0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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发货地
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上海
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背景资料
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ANGEL1 , also known as KIAA0759, is a 670 amino acid protein belonging to the CKR-4 protein family. ANGEL1 is encoded by a e located on human chromosome 14, which contains about 700 es and 106 million base pairs, making up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) e, which is one of three key es associated with the development of Alzheimer's disease. The SERPINA1 e is located on chromosome 14 and, when defective, leads to the etic disorder ?-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus on chromosome 14 and its fusion via translocation with the chromosome 19 encoded protein BCL3 may be related to B-cell malignancies.
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