产品名称

BAALC抗体

英文名称

BAALC

产品规格

50ul  100ul 200ul 

产品货号

GOY-01K0990

产品分类

抗体 / 一抗

交叉反应

Human, Mouse, Rat, Dog, Pig, Cow

保存条件

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

标记

Unconjugated

抗体来源

Rabbit

抗体类型

Polyclonal

研究领域

肿瘤 心血管 细胞生物 神经生物学

蛋白细胞定位

细胞浆,细胞膜

纯化方法

affinity purified by Protein A

性状

Liquid

浓度

1mg/ml

储存液

 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

发货地

上海

背景资料

BAALC is a 180 amino acid protein that localizes to both the membrane and the cytoplasm and ts as multiple alternatively spliced isoforms. Expressed by hematopoetic and neural cells, BAALC interacts with CaMKII and is thought to play a role in synaptic function at postsynaptic lipid rafts. BAALC may be overexpressed in acute myeloid leukemia (AML), suggesting a role in tumoriesis. The e encoding BAALC maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 es and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, conital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific es that maps to chromosome 8.