商品属性：
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产品名称
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CT27抗体
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英文名称
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CT27
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产品规格
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50ul 100ul 200ul
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产品货号
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GOY-01K1460
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产品分类
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抗体 / 一抗
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交叉反应
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Human, Mouse, Rat, Dog, Pig, Cow, Horse
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保存条件
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Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
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标记
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Unconjugated
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抗体来源
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Rabbit
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抗体类型
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Polyclonal
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研究领域
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肿瘤 染色质和核信号 信号转导 转录调节因子
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蛋白细胞定位
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细胞核,细胞浆
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纯化方法
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affinity purified by Protein A
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性状
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Liquid
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浓度
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1mg/ml
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储存液
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0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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发货地
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上海
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背景资料
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Testis-specific DNA binding protein responsible for insulator function, nuclear architecture and transcriptional control, which probably acts by recruiting epietic chromatin modifiers. Plays a key role in e imprinting in male germline, by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region (ICR). Directly binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, leading to methylate histone H4 'Arg-3' to form H4R3sme2. This probably leads to recruit de novo DNA methyltransferases at these sites (By similarity). Seems to act as tumor suppressor. In association with DNMT1 and DNMT3B, involved in activation of BAG1 e expression by binding to its promoter. Required for dimethylation of H3 lysine 4 (H3K4me2) of MYC and BRCA1 promoters.
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小鼠 IL2RB / CD122 基因全长ORF克隆 (表达载体), 带His标签
人 MAP3K8 基因全长ORF克隆 (表达载体), 带His标签
人 GDF-15 基因全长ORF克隆 (表达载体), 带FLAG标签
人 VASN 基因全长ORF克隆 (表达载体), 带Myc标签
人 DIXDC1 基因全长ORF克隆 (表达载体), 无标签