商品属性：
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产品名称
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CCDC112抗体
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英文名称
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CCDC112
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产品规格
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50ul 100ul 200ul
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产品货号
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GOY-01K1780
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产品分类
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抗体 / 一抗
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交叉反应
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Human, Mouse, Rat
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保存条件
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Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
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标记
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Unconjugated
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抗体来源
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Rabbit
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抗体类型
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Polyclonal
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研究领域
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肿瘤 细胞生物
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蛋白细胞定位
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细胞核,细胞浆,细胞膜,细胞外基质,分泌型蛋白
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纯化方法
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affinity purified by Protein A
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性状
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Liquid
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浓度
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1mg/ml
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储存液
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0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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发货地
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上海
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背景资料
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CCDC112, also known as MBC1 (mutated in bladder cancer 1), is a 446 amino acid protein. The e encoding CCDC112 is located on chromosome 5. Due to alternative splicing events, CCDC112 ts as two isoforms. Chromosome 5 comprises about 6% of human omic DNA and contains 181 million base pairs encoding around 1,000 es. It is associated with Cockayne syndrome through the ERCC8 e and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor e. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 e. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myeloous leukemias and myelodysplastic syndrome
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