商品属性：
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产品名称
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CCDC89抗体
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英文名称
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CCDC89
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产品规格
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50ul 100ul 200ul
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产品货号
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GOY-01K1795
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产品分类
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抗体 / 一抗
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交叉反应
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Human, Mouse, Rat, Dog, Pig, Cow, Sheep
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保存条件
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Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
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标记
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Unconjugated
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抗体来源
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Rabbit
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抗体类型
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Polyclonal
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研究领域
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细胞生物
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蛋白细胞定位
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细胞核,细胞浆
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纯化方法
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affinity purified by Protein A
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性状
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Liquid
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浓度
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1mg/ml
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储存液
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0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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发货地
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上海
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背景资料
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CCDC89 is a 374 amino acid cytoplasmic and nuclear protein that interacts with HRT1 and belongs to the CCDC89 family. The e that encodes CCDC89 consists of more than 2,000 bases and maps to human chromosome 11q14.1. Chromosome 11, which comprises approximately 4% of the human ome, is considered a e and disease association-dense chromosome. The chromosome 11 encoded Atm e is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB e mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 e. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded es.
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