商品属性：
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产品名称
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CGREF1抗体
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英文名称
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CGREF1
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产品规格
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50ul 100ul 200ul
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产品货号
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GOY-01K1309
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产品分类
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抗体 / 一抗
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交叉反应
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Human
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保存条件
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Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
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标记
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Unconjugated
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抗体来源
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Rabbit
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抗体类型
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Polyclonal
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研究领域
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细胞生物 细胞周期蛋白
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蛋白细胞定位
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分泌型蛋白
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纯化方法
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affinity purified by Protein A
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性状
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Liquid
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浓度
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1mg/ml
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储存液
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0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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发货地
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上海
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背景资料
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CGREF1 (cell growth regulator with EF-hand domain 1), also known as CGR11, is a 301 amino acid secreted protein that contains two highly conserved calcium binding EF-hand domains, which are required for mediating cell-cell adhesion. Induced by p53, CGREF1 is able to inhibit cell growth in various cell lines. CGREF1 is encoded by a e located on human chromosome 2, which houses over 1,400 es and comprises nearly 8% of the human ome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 e, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 es. Additionally, an extremely rare recessive etic disorder, Alstrom syndrome, is caused by mutations in the ALMS1 e, which maps to chromosome 2.
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