商品属性：
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产品名称
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CHFR抗体
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英文名称
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CHFR
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产品规格
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50ul 100ul 200ul
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产品货号
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GOY-01K0937
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产品分类
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抗体 / 一抗
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交叉反应
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Human, Mouse, Rat, Rabbit
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保存条件
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Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
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标记
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Unconjugated
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抗体来源
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Rabbit
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抗体类型
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Polyclonal
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研究领域
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肿瘤 细胞生物 染色质和核信号 细胞周期蛋白
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蛋白细胞定位
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细胞核
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纯化方法
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affinity purified by Protein A
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性状
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Liquid
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浓度
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1mg/ml
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储存液
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0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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发货地
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上海
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背景资料
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A number of human cancers are sensitive to mitotic stress, implying checkpoint defects. Many proteins that contain forkhead-associated (FHA) domains are cell cycle checkpoints and CHFR is one such protein. It has a FHA and ring finger domain within its N terminus. Within its C terminus, CHFR contains a cysteine-rich region that did not display significant similarity to any protein in the Bank database, but is highly conserved between humans and mice. It has been concluded that CHFR defines a checkpoint that delays entry into metaphase in response to mitotic stress. It has been found CpG methylation-dependent silencing of CHFR expression occurs in 45% of cancer cell lines, 40% of primary colorectal cancers, 53% of colorectal adenomas, and 30% of primary head and neck cancers.
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0.1mL×10 BL21(DE3)pLysS化学感受态 BL21 (DE3) pLysS Competent Cell -80℃保存 0.625-40 ng/mL ELISA Kit for Rat rMCP-2
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