商品属性：
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产品名称
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Complement C4 gamma chain抗体
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英文名称
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Complement C4 gamma chain
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产品规格
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50ul 100ul 200ul
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产品货号
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GOY-01K1201
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产品分类
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抗体 / 一抗
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交叉反应
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Human
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保存条件
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Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
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标记
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Unconjugated
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抗体来源
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Rabbit
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抗体类型
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Polyclonal
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研究领域
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细胞生物
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蛋白细胞定位
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分泌型蛋白
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纯化方法
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affinity purified by Protein A
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性状
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Liquid
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浓度
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1mg/ml
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储存液
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0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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发货地
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上海
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背景资料
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This e encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the anti-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This e localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this e cluster t, such that individuals may have 1, 2, or 3 copies of this e. Two transcript variants encoding different isoforms have been found for this e. [provided by RefSeq, Nov 2011].
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