商品属性：
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产品名称
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DNA polymerase eta抗体
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英文名称
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DNA polymerase eta
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产品规格
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50ul 100ul 200ul
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产品货号
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GOY-01K1715
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产品分类
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抗体 / 一抗
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交叉反应
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Human, Mouse, Rat, Rabbit
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保存条件
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Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
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标记
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Unconjugated
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抗体来源
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Rabbit
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抗体类型
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Polyclonal
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研究领域
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细胞生物 转录调节因子 表观遗传学
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蛋白细胞定位
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细胞核
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纯化方法
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affinity purified by Protein A
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性状
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Liquid
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浓度
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1mg/ml
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储存液
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0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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发货地
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上海
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背景资料
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DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. May play a role in hypermutation at immunoglobulin es. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity. Targets POLI to replication foci.
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