商品属性：
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产品名称
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Dnmt2抗体
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英文名称
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Dnmt2
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产品规格
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50ul 100ul 200ul
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产品货号
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GOY-01K0187
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产品分类
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抗体 / 一抗
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交叉反应
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Human, Mouse, Rat, Pig, Cow, Sheep
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保存条件
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Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
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标记
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Unconjugated
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抗体来源
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Rabbit
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抗体类型
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Polyclonal
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研究领域
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细胞生物 信号转导 表观遗传学
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蛋白细胞定位
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细胞核
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纯化方法
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affinity purified by Protein A
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性状
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Liquid
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浓度
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1mg/ml
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储存液
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0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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发货地
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上海
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背景资料
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Methylation at the 5'-position of cytosine is the only known naturally occurring covalent modification of the mammalian ome. DNA methylation requires the enzymatic activity of DNA 5-cytosine methyltransferase (Dnmt) proteins, which catalyze the transfer of a methyl group from S-adenosyl methionine to the 5'-position of cytosines residing in the dinucleotide CpG motif, and this methylation results in transcriptional repression of the target e. The Dnmt enzymes are encoded by independent es. Dnmt1 is the most abundant, and it preferentially methylates hemimethylated DNA and coordinates e expression during development. Additional mammalian Dnmt proteins include Dnmt2 and Dnmt3. Dnmt2 lacks the large N-terminal regulator domain of Dnmt1, is expressed at substantially lower levels in tissues, and is likely involved in methylating newly integrated retroviral DNA. Dnmt3a and Dnmt3b are encoded by two distinct es, but both are abundantly
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30次 一站式蛋白质非变性PAGE套装（低pH 缓冲液套） One-Stop Protein Native PAGE Pack 常温保存（上样液需要-20℃保存） 0.156-10 ng/mL 人甘露聚糖结合凝集素相关蛋白2(MASP2)ELISA试剂盒
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重组人 EphA7 / EHK3 蛋白 (His & GST 标签)
重组人 AMPK (G1/B1/A1) Heterotrimer 蛋白
重组人 VEGFR2 / Flk-1 / CD309 / KDR 蛋白 (His & GST 标签)
重组小鼠 CSNK2A1 / CK2A1 蛋白 (His & GST 标签)
重组人 FGFR2 / CD332 蛋白 (aa 400-821, His & GST 标签)
重组人 DCAMKL1 / DCLK1 蛋白 (aa 1-705, His & GST 标签)
重组人 CHK1 / CHEK1 蛋白 (GST 标签)
重组小鼠 NEK3 蛋白 (His & GST 标签)
重组小鼠 CSK / C-Src kinase 蛋白 (His & GST 标签)
重组人 MKK6 / MEK6 / MAP2K6 蛋白 (207 Ser/Asp, 211 Thr/Asp, His & GST 标签)